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It takes a bit ot tuning for the specific user but it'd include this sort of thing: All fonts as 25 point, black on white. Except links which are 28 point white on black and display: block.
Makes some sites look weird to a visually normal user, but they work well and can be navigated by a user with reduced vision.
Other sites, the ones not using fluid layouts, well just fuggedaboutit. You just get a jumble of text elements piled on top of each other. That is easy to interpret as: "Go away you inadequate person. We don't sell to your sort".