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I open this page using browsers and it looks fine.
Then I validate the page and it is full of markup errors... I think hundreds of lines of errors.
I looked at the source code and conclude that it is almost impossible for me to make it DTD compliant given my limited knowledge in HTML.
What I want to know is, will this page affect my overall site in terms of SEO?
Just be sure the site navigation is not disrupted by the 'bad' page.
Also look at the page in different browsers; you may find that it simply does not work, allowing you to offer it as a downloadable Excel file on a good HTML page.
If it does 'seem' to work, then it may be worth reading those reports; you'll almost certainly find that many of the hundreds are the same error repeated hundreds of times, often easily fixed with find and replace.
In genral, SEs do not validate pages, or worry about validation for its own sake - but a poorly validating page will often show badly in some browsers, and may be unreadable to many readers, or those with visual problems.
Plus, if it stops the spider spidering, you are in trouble!