Forum Moderators: martinibuster
This doesn't necessarily mean that the 300x600 works better than a 300x250, IMO. Most changes are good changes since users become blind over time to the ads so when you make a change you will see a positive spike in CTR. However, this usually lasts for a short amount of time (anywhere between 2 weeks to 2 months) depending on a few things like if you have a lot of return traffic. Then you need to change it up again and so on.
I have got AdSense on my forum so regular members probably would click on an AdSense unit if it interests them. But if you only have articles then I think it's going to be new visitors who are more likely to click. Therefore unless they are used to seeing AdSense on different sites they visit, I don't think it really matters whether you change them on a regular basis.
I stopped using responsive ads ages ago, I just don't see any need for them. Let's say you put a responsive ad at the top of your content. On a desktop it will normally display as a 728 x 90 banner. However, a mobile phone it will normally display as a rectangular unit around 300 x 250. So you might as well use an unresponsive 300 x 250 unit which gives you more control. I don't actually think the banners work very well at the top of your content, you are much better off using either a 300 x 250, or a 300 x 600 unit amongst the content.