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I also wanted to give you a heads up that soon we'll be setting the default font size a little bit bigger based on your feedback that sometimes the text ads on your page are hard to read. I'll keep you posted.
Anyway, VOILA! You can now experiment with font sizes for the text ads in your account. There are more details in the blog post we put out on the topic.
From our perspective, poor performing pages are now doing much better. Top performing (CTR) pages seemed to stay the same.
But overall we are very happy with the change.
I have seen no difference between medium and large fonts. (Veranda)
With the amount of emails I receive from visitors about the site, there is no way an advertiser would want to block traffic from it.
My income dived from 1st April - before the font size change.
I tend to think that the larger font size looks a bit ungainly. More so on one of my sites which is more 'stylishly' designed than one of the others (which is butt ugly, to be honest). Earnings are down on both of them in recent months. Even allowing for it being a quiet time of year.