Somewhat vague answers...but to summarize the important points:
* The disavow tool is applicable to Penguin hit sites, but doing a reconsideration won't help in this case
* You should attempt to remove links and not just to diavow links because apparently google can look at your history:
"In particular, Google can look at the snapshot of links we saw when we took manual action. If we don’t see any links actually taken down off the web, then we can see that sites have been disavowing without trying to get the links taken down."
* Google canonicalizes url variations well, but for pages with index or trailing slash variations, you might want to include all to be safe
* Several week delay to several months (note he didn't say if this was for Penguin)...this was horribly vague
* Lop off the www variant to get the www.domain.com/badlinks.html and domain.com/badlink.html
* Disavowed site data won't be used that much for spam data. "We may do spot checks, but we’re not planning anything more broadly with this data right now."