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Of course, there are compatibility issues with this, but for nonessential features or controlled environments, this could be very useful.
The best online resource (where I found out about this) seems to be: http://ashleyit.com/rs
Feel free to remove that link if you need to.
I also think this is a very interesting topic. I've experimented with Brent's libraries and they work very well.
There's a new technique discussed at dotvoid [dotvoid.com], it requires a dom browser but also is very interesting.
Here's another interesting article on Remote Scripting with IFRAME [developer.apple.com].
With NN4 you can dynamically load a file into a Layer object - just like an iframe.
The iframe technique requires that the remote page call a function in the original page. Tim Scarfe [developer-x.com] and Aaron Boodman [youngpup.net] have developed a technique where this is not required (IE and Moz only). See the project at Tim's old site.
But if you need cross-browser RPC's, you just can't beat Brent's work.