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Click fraud is a much discussed topic here on webmasterworld. Click Fraud is pervasive, and I am not sure how much control really exists to prevent it. In my opinion: You are best advised to watch your PPC results and costs, carefully, (like every other day, if not every day) and stick to the majors: Google and OV and maybe FindWhat.
All others, no matter what they say, are suspect. And so even are the ones I mention. I have read these posts on this subject here, for years, and I don't see any hope for much more than each advertiser's own individual vigilence, and reaction to suspicious activity and charges, by lowering bids, or leaving, but little hope in getting the PPCs to react.
One quick note on getting replies, be sure you aren't losing the support replies to a spam filter. That seems to be a fairly common ailment for a lot of users.