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Adsense horizontal AdLinks are my best performing ad units. I have them on most but not all pages across several websites. I have 120x600 skyscrapers on a much smaller subset of pages. In general, non- AdLinks ad blocks don't work well for me.
Between YPN and Adsense, here are my alternatives:
--horizontal AdLinks (most pages)
--120x600 skyscrapers (some pages)
--good contextual ad matching
--okay EPC and eCPM
--no ad links (and can't use Adsense AdLinks on same page with YPN)
--120x600 skyscrapers (very few pages)
--mediocre to abysmal ad matching (ruined in many cases by my inability to squelch those infernal, off-topic RON ads!)
--so far 0% CTR
--reportedly higher EPC than Adsense, but I can't say for myself
With these tradeoffs, I have to decide in favor of Adsense.
If YPN were to introduce the ad block most effective for me--horizontal ad links--I would reconsider, and implement YPN adlinks-skyscraper combos on more pages.
But until YPN introduces (horizontal) ad link units, their ad program has little appeal for me.