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Sadly for a client, not for me. They run CAD/CAM so needed at least one of these machines for their designer. They've since ordered 2 more 'cos they're so impressed with the performance! ;)
I had checked before I bought the kit that all devices had drivers for 64-bit Windows, and they did. Put it all together and it worked great - almost.
It had intermittent BSOD's, sometimes a couple in a day, sometimes a couple of days without one. The errors were a mix of IRQL_NOT_LESS_OR_EAQUAL, PFN_LIST_CORRUPT, and a couple of others along similar lines. Normally the first thing I go for for intermittent errors is either overheating or dodgy memory. Wasn't overheating 'cos I built it with 4 extra silent chassis fans with dust filters (they work in an insustrial environment which really doesn't do them any good).
So, tested each stick of RAM individually fine. Put it back together and spent up until week before last unplgging things, swapping bits out. Finally found Asus had updated BIOS from 0705 to 09something, notably 2 of the updates are for 'memory compatibility', particularly when using 4 DIMMs, and one for NVRAID.
It's been running a week and a bit now with no errors, I've still got my fingers crossed but looking hopeful - I can finally charge them for it now!
As for your problem, I'm assuming it's an established system...
Check if it's installed any driver updates...
Check it's not overheating - a little utility called Toast is great for system heat/stability tests but don't run without a temp monitor...
Check the RAM, Goog something called Memtest86+, you can download a free bootable CD for RAM testing, it's never failed me...
Check your heatsinks for dust - if they get clogged they will overheat even if the fan is still spinning - I killed a nV 6800GT like that...
Let us know how it goes!
It's a system less than 9 months old and seems to be stable, until now.
I went through to all the connectors last night to ensure they'd mated correctly. No apparent problems.
Dust - I cleaned out what was there, although it wasn't much, it could reduce the cooling efficiency.
I'll keep monitoring.