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Directories that offer 'multiple links' are telling you that they are there primarily for the SEs - which usually means they are pretty useless for SEO - and a risk.
Just the name 'link directory' says "I'm locked into a 2003 mind set", and should make you look more carefully.
Recprocal links, MFA and adsense - I totally agree. Avoid.
Read the text on their 'submit page' - that usually gives a fair idea of the owners intentions.
*humor categories are exempt from this warning; insert instead "if it's full of sites that DON'T make you laugh, don't submit. ;)