Start out with high CTR keywords. Don't start off with a bunch of keywords and ad groups. Create ad groups with ads that match the keywords in them. Create landing pages just for PPC and have the keywords on that landing page. Set up analytics with the detailed kw filter.
In my experience , this is a result of manual black list of domain. Even if you add tons of new content etc etc .. the domain is toast, unless you can convince the QS review team to remove the blacklist thru. manual review.
It has nothing to do with setting up a campaing 'right' or 'wrong'. It is a factor out of one's control.
Now, be careful..if you start off with a new domain with same content, you risk the adWord ban.