I've taken one of our more popular pages and converted it over to YPN. All the rest run Adsense. On the YPN page the CTR is about 15% of what the Adsense ads are. At first I thought it may be the quality of advertisers or lack of different advertisers. But after a bit more examination I can't really see the logic behind why the CTR would be so different. Then I thought... perhaps adsense is counting the entire ad block as one impression and YPN counts each indvidual ad IN the ad block as one impression.
So if I have two ad units with, four ads; adsense would count them as 2 impressions but YPN would count the same configuration as 8 impressions. Is it possible that could explain the huge difference in CTR between the two? Other than that, I have no clue... I could see maybe 50% of the CTR given the ad quality but I just can't explain 15% of the CTR any other way.