A few years ago, Matt came out on video and famously held up his note paper and sticky notes and showed us all what is "probably too much".
At that time no one was talking mobile devices and for that matter it was basically impossible to get anyone at G to commit to what size screen THEY were even using to determine the algo percentage (even our personal reps at GAdsense had no idea - although a mental memo at the time confirmed they all had 1200x800 monitors.)
So now enter teeny tiny mobile screens, mobile friendliness and the like, and are we in even more of a quandary? Can a page get penalized for too many ads on a mobile, but not a desktop? Without testing every single page on every mobile device can we rest assured we're not accidentally letting too many ads slip above the fold to anger G when a mobile user flips his device sideways and only displays the top 320 pixels, where 50 of them (vertically) are our logo and anywhere from 90 to 250 of the pixels are an ad that would be ok on a laptop?
Do we need to assume the worst common denominator and make sure NO ads are ever above the 1024 pixel level at all widths?