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I came back 10 days later and I thought that the problem might have automatically fixed itself... Of course it hadn't... Further investigation revealed that the majority of sectors on my HD had been somehow corrupted (still don't know how!). Clean install of XP Pro and format the HD... The pain... The pain!
Now I've lost all work for clients, all my digital photos, all my MP3's and all my app's and drivers will have to be re-installed.
I will back up my work. I will back up my work. If you don't already - consider my tale of woe - and back up all your work.
Now everything is backed up every day to a removable HD in a RAID array, which is stored safely each night.