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In some it might bring in better ads, but they might also pay less.
In other markets you may end up looking at nearly empty ad blocks, or even a lot of PSAs.
lt also depends on which ad blocks you are using. I'd be less worried about empty space if I was using an ad block that displayed 2 or 3 ads than if I was using a block that displayed 4 or 5 ads.
That said, I blocked *bay and their affiliates and the result was much less than desireable at the time. I ended up with a lot of empty space.
But I'm in a fairly low CPC area in general. Perhaps in a higher priced area with more advertisers it wouldn't matter as much.
If you block an ad that adsense is displaying, you will get an ad with a lower earnings per click than the ad you blocked. Adsense displays ads with the highest costing ads per click and then down the list. That is the point of bidding for keywords, if you bid higher, you have a better chance of being picked for selected keywords.
If you block an ad that you see on your page, adsense assumes that the ad is showing is a good match, and has one of the top 4 highest cost of all ads that fit the criteria of your page. If you block the ad, your earnings per click for the ad that will replace it will be lower, maybe a penny lower, maybe a dollar lower.
On the other hand if you block an ad that has little to do with your page, and get in a new ad that has a better click through rate, the tradeoff of banning the higher paying ad with the increaes in CTR for the new ad might yield more earnings.
Blocking an ad will result in a new ad that has a lower CPC, unless new advertisers come along at the same time you are doing that and bid more than the ad you blocked. Your CTR MAY go up if the ad is more relevant to your pages, and visitors find it more attractive to click on.
That's not the way I understand the ad positioning in Adwords/Adsense.
As I understand it Google uses a forumula based on the CPC and the CTR to determine where an ad places in the ad block.
So it's possible that a lower cost ad with a higher CTR will place above a higher priced ad with a lower CTR.
Therefore it might be possible (how likely I don'tknow) that blocking a popular, but cheap, ad will allow a more expensive ad to be shown, even though it has a lower CTR.