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Ditto for booze, guns, and other topics that are given the no-no in the AdSense TOS. There's an obvious difference between an article on shotguns in the outdoor section of the PODUNK PRESS-CHRONICLE and a site called assault-weapons-advocate.com, or a site devoted to moonshining and a review of single-malt whiskies on a site devoted to the epicurean lifestyle.
Just use common sense, and if you still aren't sure, ask AdSense Support before you apply for an account.
there's obviously a difference between a site that mentions sex and drugs and one that's specifically about sex and drugs
Not too sure that Google sees it this way. One (in hundreds) of my pages (on a travel site) mentions that there are beaches where you don't need to wear clothes. Really harmless stuff....PSA only...sigh!