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(I am asking because I am looking to create a complex user interface in ASP.Net and they have a requirement to be cross platform compatible Linux/Windows/Mac - I am not worried about text browsers and javascript disabled browsers)
One thing to consider is using regular form elements that have runat="server" attribute instead of the asp:form elements. Those can make strange things happen cross-browser. There is a thread back here somewhere, where the server was sending down a different element for opera. I will try and hunt it up. I think once the switch was made to a non-asp:form element it worked.
I have not come across anything yet that there was not a work around. Since you know the browser compatability well, I don't think you will have any major issues.
Honestly the web forms have done pretty well. I haven't really had any problems with datagrids either.
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here is a thread about a browser issue:
[webmasterworld.com...]
It does seem to be quite rare.
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