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The type of business may make a difference. If microsoftusa.com is selling software, most courts might construe that confusion could exist. However, if you were hand a new micro-weave knitting technology and put up a textile sales site called microsoftblankets.com, you might be able to hang onto it. OTOH, large companies can afford good lawyers, and lots of them - right or wrong don't always count.
...as the other party registered the domain name before you acquired the respective trademark, your case may not be as straightforward as it would otherwise be. Your decision to trademark could potentially be seen as a knee-jerk reaction and harm your case.
As ever with cases like this, consulting with a domain savvy lawyer would be the best course of action to find out exactly where you stand.