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I usually recommend Constant Contact. I've been using them for years without fail.
I would like to mention that Constant Contact are fairly strict with their services so if your list is not Opt-In, don't even think about signing up. They'll "can you" if you violate their terms of service.
It's free in a manner of speaking.
You are correct. But, there are some associated risks that you need to prepare for when sending from your domain.
If you are going to do this in-house, it is suggested that you research the various laws that apply to email lists, particularly the CAN-SPAM law. Every single email you send out should have certain elements as part of that law.
The biggest risk you'll face is being reported for spam. Once people start reporting you, things get a bit more difficult to manage as you will now be chasing the blacklists to get your domain removed.
With 75,000 Subscribers, your rate of spam reports will be enough to cause potential issues if you do this in-house. Just a word of caution...
How can I check on my "blacklist status"?
That is what is referred to as "reactive" email marketing. ;)
What you should really be doing before even attempting to send from your domain is making sure that your DNS is in order. A few hiccups in your DNS settings and your mail is apt to get filtered to Bulk/Junk.