It may cause problems with SE's as they may adhere strictly to the rules that a host name should be 'a-z', '0-9' or a '-' characters only - this was set in the very early days of the internet - 1982 or something in an RFC. Since then lots has changed, proposals and some support for internationalised domain names but not necessarily the code in XYZ search engine.
Is there anything to stop you using
www.word-word2.example.com? ie. a hyphen rather than an underscore?