Recently there were two instances in the Google Forums, both confirmed by a Google employee called "TheJack", where a ranking drop for a site was caused by an internal error at Google - a mistake that "misclassified" the domain.
Even if it's a rare occurrence, this stuff does happen and it's disturbing for sure. And according to TheJack, in some cases, if you are having issues with your rankings, it's best to post them at Google's forums. That just doesn't work for me at all. I would still hope that a Reconsideration Request can do the job.
Google Misclassifying Some Sites As Parked Domains & Booting Them From Search Results? [seroundtable.com]