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I have an Adsense tracker that tracks all of my impressions and clicks (as well as referrer, ad size, colors used, advertisers link, and more). I've noticed my CTR as high as 300% sometimes. How? Basically, a visitor will come to one of my sites (1 impression), click on an ad, then come back and click again (2 clicks). Whether they open a new window or just hit the back button, I don't know, but I haven't seen more than 3 clicks per IP. Maybe Google has a limit (or security) on how many ads a user can click on.