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It's funny you mention this. I was in Florida for a few days in March and didn't really pay attention to Adsense. Almost every day was a record day, one day was unvelievable.
Now I am no longer on vacation and back to mediocrity. Maybe I should take a permanent vacation.
But usually I find Sundays to be really good days for me. Probably because most people have more free time on the weekend to surf the internet, but every market is different. If my web sites catered towards mortgages, I'd probably have more people searching during office hours. Every market produces different results.
I use one of those Adsense revenue utilities that sit in the system tray. Set to check on the quarter of the hour every half hour. It's much faster than going to Google to check. I now use it more as a way to monitor my sites to make sure they are up than know how much I'm making.
If the revenue one hour drops dramatically from the averages, I know I need to bug my provider to get it back online. I've lost hundreds of dollars in the past because I wasn't monitoring the site, and the provider wasn't paying attention to down time.
Google has updated their Adsense interface a few times; it seems each time they do, the utility upgrade needs to be downloaded and reinstalled. Small inconvenience for a site monitor. The price is about the same as many other utilities, $29.95.
It's a great way to break the Adsense income update addiction! :-/