Forum Moderators: phranque
And remember that screen resolution does not equal window size -- as the user of a 1600x1200 res monitor, I'm sure you don't always run your browser at full screen, so you know what I mean.
The answer is "No" it is not reasonable, because nearly 40% of current users are running a monitor set for 800x600. And maybe 45% or so are running at 1024, so you've got to account for both groups, and do so very intentionally.
This is based on the public stats at W3Schools [w3schools.com] and my own stable of clients whose stats I watch regularly.
In fact, it's a fascinating culture-wide trend in the US -- everything is being offered in both very large and very small versions. This includes soda (6-oz cans and 50-ounce "big gulps"), candy bars, and even vegetables! Wired Magazine had an article last year about this trend to grow at the extremes in size, but shrink in the middle. I can't find it right now, but I think they called it the "Well Shaped Curve".
And so the need grows for liquid, fluid design principles that are device independent.