Forum Moderators: phranque
I, like geoapa, typically use 740px as my default for most sites.
The important thing to remember is if you have anything that a visitor may want to print out, only the first 660px will print on a fixed design. I generally use a 120 pixel right column for skysrcapers, then the primary content will print in full.
It appears that the 800x600 'safe' size is 744px (so 740px should be fine). The latest display stats across all our sites is 44% for 800x600, 1024x768 or more is 49%, 640x480 is 2%, and 5% for all others.
Of course I can't argue with Nick_W either. When possible, a fluid design can be pretty effective as well.
Whether fluid or fixed, I always like to play with the various display properties to see what each design looks like at 800x600 and above.