You mean use of keywords in domain won't be the problem ? Actually I am asking this because we all know that there was an Exact Match Domain update by Google [2 yrs ago]. And this update devalued the ranking of websites which contained the keywords in their domain, definitely quality issue was there.
EMD update has not devalued and dropped rankings of domains that has keywords in it but it dropped domains with keywords in it and low quality content. There are still several several sites ranking high and getting preference from the Big G which have exact keyword match domain because their content quality. If you will focus on high content quality especially if you will update it on regular basis say then it really won't be an issue.
An advice: Focus on quality and making a better website instead of search engine rankings.