The answer is impossible to give in a "general" stance as it will be all over the map. I use/d both on various sites Adsense blows YPN away in some categories, while YPN blows Adsense away in others, even with a lower relevancy. There is no stance of "all things being equal" - because the keyword/industry will severely change results of various users. We don't allow specifics here, so the questions can't really be answered comprehensively. All you can do is test it out on your own site and see which one works best for you.