Dijkgraaf - 10:49 pm on Jul 1, 2010 (gmt 0)
Of course it is possible.
Rankings for my site on the single major keyword
Google=#3 (Get #1 with a two keyword search).
But as I haven't done any SEO (as it is not a commercial/money making site) I can't give you any tricks to achieve it apart from having lots of relevant contents on the site.