lucy24 - 7:07 pm on Dec 13, 2012 (gmt 0)
it becomes difficult to maintain a big file
I hope that was a typo for "big site" because otherwise I am even more confused than my natural state ;)
It's not that long since I followed-up every htaccess edit with a quick view of some random page just to make sure I hadn't introduced a 500-class typo. Now I only do it with large complicated changes.