I would not be so quick to discount all of GAS' recommendations. Some do work, although I imagine a lot of that success is a numbers game rather than someone actually looking at your site and thinking mmmmm.
What I do wish I had done much earlier is to block certain types of ads. I received a lot of comments/complaints about some of the ads people were seeing on my main site. Of course what they see in one part of the world and what I see maybe two different things but I understood. Since then I have blocked any type of ad that some might deem offensive.
I suggest read what GAS has to say, think it through test if necessary but always consider your viewers first.