netmeg - 8:09 pm on Apr 17, 2012 (gmt 0)
On my sites, the 320x50 is either at the very top center or the very bottom center of the pages.
I don't mean to make you nervous, but these are the things that go through my head when I'm planning my designs.
I don't think AdSense is quite caught up to the technology yet. I think they *think* they are, but they aren't.
And if I'm gonna err, I'm gonna err on the cautious side.