I was thinking of applying for Federated Media, but I don't know if I'd get accepted or not. A lot of people in my industry use an industry-specific ad network, and they contacted me to join, but they couldn't give me specifics on the average CPM, etc., and it would be a huge pain to remove Adsense and switch to that network just to see if it was better. I have a feeling it wouldn't be better, but I've heard Federated Media pays well.
A few years ago I tried another ad network that is fairly big, and the CPM was less than Adsense (even now that Adsense is sucking for me). I'm curious too if anyone has tried other ad networks (if they have, and they work better than Adsense, then I guess they wouldn't be here on this board).