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martinibuster - 7:48 am on May 13, 2010 (gmt 0)
Below the fold on an informational site can be a prime spot if the article is about the benefits of a blue widget and the ad is about a sale on blue widgets. In my experience the CTR and conversion on affiliate ads/links placed at the end of articles in this manner can be fanstastic.
Higher up on the page might be the best place for advertisers in general, but not always.