For now I want nothing to do with "interest based ads" because my traffic is primarily from search. When someone searches for a kitchen widget they want to buy a kitchen widget and are less likely to click on ads about widget sports ya know?
I believe that this will hurt publishers who want site targeted ads, not interest based ads, because they're traffic is laser targeted via search engine.
edit: If I can't make sure my site gets only ads about my site topic I SHOULD be able to turn off Google's new interest based ads. NOT being able to has me measuring options in case earnings drop.
[edited by: JS_Harris at 3:22 am (utc) on Mar. 16, 2009]