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Thez - 9:01 pm on Nov 9, 2005 (gmt 0)
I noticed that placing ads inside content, in the top left side and middle gets the most clicks for me. No borders, same link/text/background color in ads works the best. If the ad is before or after the actual content of the page, the clicks tend to be low. Nowadays when building a page I start by making a "header" or "introduction", then adding a leaderboard or a rectangle unit depending on the page's layout after that. After the ad comes the actual content, with maybe an ad in the middle "inside" the text. On some pages where I had first a leaderboard, then the content, switching places with the leaderboard and the header sometimes even tripled click throughs for that unit.
I've also experimented a lot with different colours and placement.