No, but what's the ratio of ads to content on your page?
I have used AdWords to drive traffic to pages with AdSense on them, but never had more than one ad block and one link unit on the page, and the content was a MUCH larger percentage of the page than the ads were. On the pages where I have more ads running (either AdSense or affiliates) I don't tend to use AdWords for those.
Part of the problem here is Google's terminology. When they say "this page is not highly relevant" they are not telling you relevant to what, so most people of course take it personally. I don't believe they are trying to tell you that the page is not relevant to the search, and that's how a lot of people take it. I think they are trying to say that the page needs to be relevant to the keywords in the ad group, and the text in the ad. It's a nitpick, but it's an important one.