CainIV - 6:03 am on Jun 28, 2013 (gmt 0)
My advice would be to remove anything that doesn't look natural or editorially given, is irrelevant to what you do or all out looks low quality or paid.
Low quality links are links on websites that have low authority factors, low inbound links, low social metrics or plain low quality content. Getting good with tools you can learn how to assess these factors very quickly and make distinctions.
It's better to remove than disavow.
Begin actively, monthly, monitoring your back links and staying on top of new links in the same fashion.
Always have a plan to replace lousy links with high quality naturally given links.