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Whitey - 12:22 am on Mar 19, 2013 (gmt 0)
It's worth revisiting this video from Matt Cutts on lifting penalties [youtube.com...]
Here and in other instances, MC mentions that for some sites, where remedial steps are too difficult to action, it might be better to start again. In the case of Interflora it was easy for a large resourced company to identify the tactics and placements of offending links, and/or take down the offending recipient landing pages and re index new URL's as another option.