ZydoSEO - 4:09 am on Feb 7, 2013 (gmt 0)
Your URL structure has zero effect on how many clicks away from the home page a particular URL "lives". I can have a URL that is example.com/L1/L2/L3/L4/L5/L6/L7/L8/L9/L10/page.html. If I link to it anywhere on the home page then that page is exactly 1 click away from the home page... not 11 as the URL structure might imply.
"Clicks away from the home page" is ALL about internal linking of your pages and has absolutely zero to do with your URL structure.