g1smd - 4:15 pm on Jun 24, 2012 (gmt 0)
Yes, as long as it is simple to identify which requests will be served by static files and which by wordpress.
Hopefully all the URLs to be served by static files have some common element/pattern within them.
I've used a similar rewrite to temporarily replace a CMS generated page with a static file for a short time. The last time was when a new product was added to the CMS pages, but not yet available. The rewrite was installed serving the content from a static page with much more basic "coming soon" information. On launch day the rewrite was removed revealing the CMS generated pages.