No there isn't really anything that makes the content hard to find imho.
I have a header with logo that incorporates 6 small tabs to important sections of the site (106px height total). Content starts straight below this with a nav bar to the left featuring further links to internal pages.
I've been racking my brains and the only thing I can come up with is I also have a forum as part of the site. Under the forum header I have a 728*90 Adsense block which is fairly standard placement. Even that though is only about 10% of the area above the fold at my resolution.