Robert_Charlton - 4:14 pm on Nov 3, 2011 (gmt 0)
I myself dislike in-text ads like Vibrant media's immensely... a completely personal thing... because they interfere with my use of a page. It's not clear whether similar reaction from other users will affect Panda.
Additionally, ads from multiple sources can end up slowing page loads down quite a bit, particularly in combination with social media feedback buttons and many things that are being tacked onto a page.
All this beyond the file size of the page and its images. The layout of the rest of the page, IMO, enters into it as well... how cleanly separated all the content elements are and how easy the page is to look at and use.
So, it's hard to ask the question in isolation and simply single out just one kind of ad as a ranking factor. It's a combination of many factors, affecting the usability of the site.