Absolutely international page speed can affect rankings. The center of the universe is in California where googlebot originates for all sites, the further you are from there the more important it is for your site to perform.
The above is however tempered by visitors who use Google products like Chrome, pagerank button, or on sites that use analytics or adsense. Those visitors report back to Google how long it took for THEM from THEIR location... which adjusts your page speed average in that location.
You need to be fast from both California and from your local visitors, for best results use both a California based and local based CDN.