I'd be careful in this instance to avoid "back to back" duplication. It "looks" a bit unusual at times and may be a signal if other things are present. That type of "back to back" replication may go against how those elements should work in unison and in a sequence.
I think that is a good thing. Something is telling you that would be the best option. Intution maybe? Gut instinct? ;)
Your <title> is "very succinct". Your meta description takes the <title> and expands on that. Those first two areas in the content area are most likely an <h> and an opening <p> or something similar. The <title> and meta description should be a synopsis of what is taking place at the very beginning of that content (front-loading).
Think of it this way. You have "one chance" to get your message out there. If you had 200-250 characters to work with as a guideline for writing the <title> and meta description, how would you do that to "attract" the most "visual appeal".
Also, keyword positioning in the elements is a factor that is all relative. Certain types of pages may qualify for something that pushes those keywords further towards the end of the <title> but the effect is a positive one in many instances. ;)