roycerus - 8:50 pm on Mar 23, 2013 (gmt 0)
Sponsorship only works in industries where showing your name (brand) is important in being chosen. Industries like higher education, hosting, beverages, credit cards will sponsor high traffic sites.
There needs to be a clear demand for the service and it should be directly related to what the consumer is reading or viewing.
For any other kind of advertising Adsense is probably the best option at this moment.