thirteen - 7:14 pm on Jul 3, 2011 (gmt 0)
Kansas City, Kansas and Kansas City, Missouri. Google is using those cities as test sites for fast internet connection. You will have the best internet infrastructure in place there for e-biz.
North Dakota is another good place. It is one of the few States that is booming. It has low unemployment, government surplus, and growing population growth. Good place to develop your own space for local e-biz.