CPC_Andrew - 6:30 pm on Feb 17, 2011 (gmt 0)
My humble opinion: Find great partners to take care of important aspects of your business. Sometimes that's hard, but ask around to your closest eCommerce friends and see what they say. Ask them for honest opinions, not dry referrals.
Delegate as much as you can. Sometimes your partners can do what you're doing better, and free up your time to concentrate on more important things in your business, and family, etc.
Teach a high school student looking for work a specialized section of your business. Kids are surprisingly tech savvy these days, and cheap :-).