MatthewHSE - 5:52 pm on May 31, 2005 (gmt 0) Of course, my own site is also pretty good, but I won't go self-promoting! ;)
I think the most brilliant layout I've ever seen is over at techpatterns.com (no personal connection). It's a CSS layout, with three columns and footer with all columns full-height regardless of actual content amount. (In other words, you can get full-height background colors without using Faux Columns.) In point of beauty, the design leaves something to be desired in my opinion, but from a strictly technical viewpoint I've never seen its equal. The design is incredibly complex to figure out, but pretty stable and effective.
Of course, my own site is also pretty good, but I won't go self-promoting! ;)