I used to work at a major directory, and I can tell you that none of us *ever* looked at metatags other than the TITLE tag when creating site listings.
Most of the people that I worked with had MLS degrees and thus were professionally trained in metadata creation. In contrast, most normal people completely suck at writing metadata. Seriously.
Our actual process: Scan the home page and a few of the subpages in order to get an idea of what the site was about, and then write a description according to the style guidelines.
So no, I strongly doubt that META Description tags or META Keywords tags are useful to editors at major directories.