The Windows 8 transition was difficult for us Win 3.0 types. We've been using Win8 since summer and began transitioning developer and marketing teams in September. The feedback is 100% positive - though it is frustrating and time consuming to learn how to get around. And there are a few driver problems with Cisco VPN, HP, etc. We have Win 8 phones and a tablets for cross-browser and UI testing. They're wicked cool.
M$ having the same UI for a phone, tablet and desktop might be a winning combination to compete with Apple. Droid can't do this because they lack market share in the desktop OS space. The iPad is a toy - a very nice toy. If M$ can get PC power into a tablet with Word and Excel they're going to gain a lot of market share and retain their dominance with Office.
Corporate I.T. has been pushed by C-level execs to deploy iPhones and iPads against their wishes. C-level types may now return to a more comfy spot. I feel bad for Blackberry.
Still, a bet on M$ is a long-shot. They've not exactly been leaders of innovation. That said, .NET is a pretty big and widely adopted development platform.
[Disclosure: we're primarily an ASP.NET development group that plays in a mid-tier - we might be a bit biased toward M$].